Bicyclic phosphate is a class of organophosphate compounds that are used as flame retardants, stabilizers and antioxidants. They are also used in spectroscopic studies. Some bicyclic phosphates, such as TBPS, TBPO and IPTBO, are highly toxic.
TBPO is an extremely toxic bicyclic phosphate convulsant and GABA receptor antagonist. It is the most toxic bicyclic phosphate known, with an LD50 of 36 μg/kg in mice.
IPTBO (isopropylbicyclophosphate, also IPPO) is a bicyclic phosphate convulsant. It is an extremely potent GABA receptor antagonist that can cause violent convulsions in mice. IPTBO is found among a group of highly toxic bicyclic phosphates.
TBPS (tert-butylbicyclophosphorothionate) is a bicyclic phosphate convulsant. It is an extremely potent GABA receptor antagonist.
Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from Penicillium moulds, principally P. chrysogenum and P. rubens. Eight species of Penicillium, in the section Chrysogena, produce penicillins. Most penicillins in...
RDX (Research Department Explosive or Royal Demolition Explosive), or hexogen, also known by other names, is an organic compound with the formula (CH2N2O2)3. It is white, odorless, tasteless, and widely used as an explosive. Chemically, it is...
Ciprofloxacin, sold under the brand name Cipro among others, is a fluoroquinolone antibiotic used to treat a number of bacterial infections. This includes bone and joint infections, intra-abdominal infections, certain types of infectious diarrhea,...
Baclofen, sold under the brand name Lioresal among others, is a central nervous system (CNS) depressant and derivative of the inhibitory neurotransmitter, gamma-Aminobutyric acid (GABA). Baclofen is a potent GABAB receptor agonist, antispasmodic,...
GABA, also known as gamma-aminobutyric acid or γ-aminobutyric acid, is the chief inhibitory neurotransmitter in the developmentally mature mammalian central nervous system. Its principal role is reducing neuronal excitability throughout the nervous...
Furosemide, sold under the brand name Lasix among others, is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease. Furosemide may also be used for the treatment of high blood pressure. It can be...
